Glucocorticoid-induced immunosuppression is linked to the dose, duration, and intensity, but the dose-dependent model may inaccurately predict the risk of opportunistic infections. We discuss details of glucocorticoid treatments to determine their effect on immune function and risk of opportunistic infections.
Editor's Choice
In the Swiss HIV Cohort Study, replacing tenofovir alafenamide (TAF) with tenofovir disoproxil fumarate (TDF) resulted in a -1.84 kg weight decrease within one year. No substantial weight changes were noted after switching from TAF to dolutegravir/lamivudine or cabotegravir/rilpivirine.
After the initial phase of the COVID-19 pandemic, hospitals reported an increase in RSV cases. We examined encounters at US pediatric hospitals and found that increased testing is likely driving the observed increase in case volume.
People with human immunodeficiency virus with both cytological anal high-grade squamous intraepithelial lesion and nadir CD4 cell count ≤200/µL face 13-fold increased anal cancer risk compared with those lacking both. Anal cancer mortality (21%) occurred exclusively among stage IIIA patients.
Best of the IDSA Journals 2023
As we usher in the new year, the IDSA journals would like to thank all the excellent authors and peer reviewers that have contributed their expertise in 2023. The Editors-in-Chief of Clinical Infectious Diseases, The Journal of Infectious Diseases, and Open Forum Infectious Diseases have each selected 5 articles that represent significant contributions in their fields. We invite you to explore the sample of impressive research online.
CID Now Offers Review Pathway for Papers Rejected by High-Impact Journals
Clinical Infectious Diseases welcomes papers that have been peer reviewed by another medical journal and were not accepted for publication, where the authors believe they can address the essential concerns identified by previous reviewers. Under this new pathway, authors can revise the paper according to the review comments they previously received and then submit the paper to CID. This new pathway is intended to speed publication and minimize unnecessary re-review of papers that previously received thorough and detailed review elsewhere.
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